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GLP-1在不同組織中具有多種作用和廣泛的治療潛力。
GLP-1 shows numerous actions in different tissues, and a broad therapeutic potential.
GLP-1的主要作用是刺激胰島素分泌并抑制胰高血糖素分泌,從而有助于控制餐后血糖波動。
The main actions of GLP-1 are to stimulate insulin secretion and to inhibit glucagon secretion,thereby contributing to limit postprandial glucose excursions.
GLP-1 可以增強飽腹感而導致體重減輕,此外,GLP-1還抑制胃腸道運動和分泌,可以充當腸胃素和“回腸制動”機制的一部分。
GLP-1 also causes weight loss by increasing satiety. In addition, GLP-1 also inhibits gastrointestinal motility and secretion,and thus acts as an enterogastrone and part of the "ileal brake" mechanism.